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KMID : 0605720020080020340
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Journal of the Korean Society of Biological Therapies in Psychiatry
2002 Volume.8 No. 2 p.340 ~ p.347
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A Comparison Study of Patterns of Comorbidity and Severity in Panic Disorder without and with Agoraphobia
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Lim Kyung-Hee
Kim Jung-Bum
Chang Eun-Jin
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Abstract
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OBJECTIVES: In this research comorbidity and severity of symptom of patients that have panic disorder without agoraphobia(PD) and with agoraphobia(PDA) were examined in order to study their nature more closely and also to help set up therapy plans.
METHODS: 70 patients were diagnosed with PD(N = 26) and PDA(N = 44) by DSM-IV. SCL-90-R was adminis-tered to panic subjects and normal control subjects. PDSS were administered to panic subjects, the statistical analysis was conducted using ANOVA, Chi-square test, student t-test, Pearson Correlation analysis. statistical significance was p < .05.
RESULTS: 1) The degree of agoraphobic fear/avoidance of PDA indicated the level to mild from moderate(PDSS score 1.46+/-0.94). 2) There was no significant difference between the two groups(PD/PDA) in there sex, age, education level, occupation, duration of illness, onset of age. 3) After analyzing the comorbidity pattern of the three groups, PDA was significantly higher score than normal control groups in all symptom level. PD had higher score than normal control groups in anxiety, phobic anxiety and psychotism. 4) PDA showed much a significantly higher score in Somatization, bsessive-Compulsive, Hostility, Phobic Anxiety, Paranoid Ideation when compared to PD. 5) There was no significant difference between the two groups(PD/PDA) in there interoceptive fear/avoidance, work impairment/distress, social impairment/distress scores. But in the severity total score, composite score, panic frequency, panic distress, anticipatory anxiety and agoraphobic fear/avoidance, PDA had significantly higher scores than PD. 6) The agoraphobic fear/avoidance item within PDA had significant correlation with Soma-tization, Obsessive-Compulsive, Interpersonal Sensitivity, Depression, Anxiety, Hostility, Phobic Anxiety, Paranoid Ideation except significant correlation with psychoticism.
CONCLUSION: As it is shown clearly in all the results, PDA had a higher level of severity than PD. It was also clarified that PDA had a variety of comorbidity. Therefore when evaluating the treatment of Panic Disorder, one has to consider the comorbidity and severity. A more positively and concentrated treatment will be needed when panic disorder is accompanied by agoraphobia.
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KEYWORD
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Panic disorder, Agoraphobia, Comorbidity & Severity of symptom
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